Dr Jamel Mankouri

Dr Jamel Mankouri

Profile

We have shown that by pharmacologically modulating cellular ion channels, we can impede the lifecycles of an array of important human viruses. My laboratory focuses on understanding the interaction between viruses and cellular ion channels in more detail. By doing so, we wish to reveal the potential of ion channel modulating compounds (many of which are clinically available) as new anti-viral drugs. 

  • Identifiying new virus-ion channel interactions.   
  • Investigating the potential of restoring the function of virus-ion channel targets as a new anti-viral strategy.
  • The role of endosomal ions during virus entry.

Career History: Post-doctoral researcher with Prof Mark Harris in the School of Molecular and Cellular Biology, University of Leeds (2006 - 2009); Post-doctoral Researcher with Prof Mark Harris and Dr Stephen Griffin (2009-2011) in the School of Molecular and Cellular Biology, University of Leeds. Royal Society University Research Fellow (2011-2019).

Responsibilities

  • School Academic Lead for Inclusive Practice

Research interests

Investigating host cell ion channel function as a novel target during virus infection

<h4>Research projects</h4> <p>Any research projects I'm currently working on will be listed below. Our list of all <a href="https://biologicalsciences.leeds.ac.uk/dir/research-projects">research projects</a> allows you to view and search the full list of projects in the faculty.</p>

Qualifications

  • PhD, University of Leeds
  • BSc, Pharmacology

Student education

Undergraduate project topics:

  • Virus-ion channel interactions and their roles during the virus lifecycle.

Postgraduate studentship areas:

  • The role of endosomal ions during virus entry.
  • What can viruses teach us about cellular ion homeostasis?

Modules managed 

  • BIOL2210 - Biological Membranes and Cell Signalling,

  • Advanced Topic Unit: Virus host interactions

Research groups and institutes

  • Microbiology
  • Virology
<h4>Postgraduate research opportunities</h4> <p>We welcome enquiries from motivated and qualified applicants from all around the world who are interested in PhD study. Our <a href="https://phd.leeds.ac.uk">research opportunities</a> allow you to search for projects and scholarships.</p>
Projects
    <li><a href="//phd.leeds.ac.uk/project/812-role-of-endothelial-mechanosensory-protein-piezo1-in-covid-19-infection-and-pathogenicity">Role of endothelial mechanosensory protein PIEZO1 in COVID-19 infection and pathogenicity</a></li>