Recent Grants

 

  • David WestheadBloodwise, A consensus definition of molecular high grade lymphoma for clinical and trial use, (12/09/19) – £102,415
  • Anastasia Zhuravleva, BBSRC Responsive Mode, Targeting SurA Dynamics: An Achilles Heel in Bacterial Outer Membrane Biogenesis, (05/09/2019) – £693,023
  • Brendan Davies, BBSRC Responsive Mode, Finding the Balance: Repression of Plant Gene Expression, (05/09/2019) – £804,571
  • Lars Jeuken, BBSRC Responsive Mode, Exploiting membrane enzymes in biotechnology: Bioelectrocatalysis and fuel cells, (05/09/2019) – £561,069
  • Ralf RichterBBSRC Responsive Mode, Understanding hyaluronan crosslinking mechanisms in ovulation and inflammation: CryoEM structural and interaction analysis of HC-HA/PTX3 complexes, (05/09/2019) – £326,437 ​​​​​​​
  • Peter UrwinBBSRC Responsive Mode, An integrated strategy for control of animal and plant parasitic nematodes through targeting a 5-HT-gated chloride channel MOD-1, (05/09/2019) – £158,960
  • Ade WhitehouseBBSRC Responsive Mode, Virus manipulation of host non-coding RNA regulatory networks, (05/09/2019) – £633,078
  • Darren Tomlinson, BBSRC Pathfinder Award, Technological evaluation and commercial assessment of a novel technology platform for pharmacophore generation, (05/09/2019) – £9,306
  • Hannah Dugdale (CO-I), NERC, Gut microbiome variation, fitness and senescence within a natural vertebrate population, (05/09/2019) – £35,026.17
  • Chi Trinh (CO-I) and James Robinson (PI, School of Medicine), Academy of Medical Sciences, Defining the spatial requirements for therapeutic modulation of signalling through FcγRIIa, (01/08/2019) – £98,000
  • Alex Breeze in collaboration with Darren Tomlinson (Co-I) and Professor Mike Waring at Newcastle UniversityCRUK Small Molecule Drug Discovery Project Award​​​​​​, Novel allosteric inhibitors of SOS-mediated mutant Ras-driven tumorigenesis, (01/08/2019) – £185,607​​​​
  • Paul Millner & Darren Tomlinson (Co-Is) with Gin Jose (PI, School of Chemical and Process Engineering), EPSRC, Photonic Sensing and Dual-mode Bio-Imaging with Rare Earth Upconversion Nanopart, (01/08/2019) – £361,818
  • Lisa Collins, BBSRC (via Nottingham University), AMR in Argentine Broiler Poultry Systems: Risks and Mitigation, (01/08/2019) – £241,338
  • Candelas Paniagua CorreasEuropean Commission, Call Mechanics, (01/08/2019) – £166,000
  • Peter UrwinBBSRC (via University of Southampton), An integrated strategy for control of animal and plant parasitic nematodes through targeting a 5-HT-gated chloride channel MOD-1, (01/08/2019) – £158,960
  • Katie Field and Co-I Peter UrwinLeverhulme Trust worth, Friend or foe; who wins in the competition for plant resources?, (11/07/2019) - £465,000
  • Darren TomlinsonCRUK (via Imperial College London), A novel therapeutic strategy for Epstein-Barr Virus-driven cancers, (04/07/2019) - £172,035
  • Ed WhiteBHF, The role of Purkinje fibres in mechanically-induced arrhythmias, (04/07/2019) - £255,054
  • Alex O’NeillOxford Drug Design, Studies of antibacterial compounds, (13/06/2019) - £210,639
  • Michelle PeckhamMRC grant in collaboration with KCL, Understanding the mechanisms underlying myosinopathies, (06/06/2019) - £671,168 FEC, £536,934 external
  • Emanuele Paci and Eric BlairInnovate UK/Freeline Therapeutics Ltd, Knowledge Transfer Partnership, (23/05/2019) - £327,348
  • Jessica Kwok in collaboration with KCL, MRC, Recovery of normal breathing after chronic paralysis, (16/05/2019) - £800,570
  • Stefan KepinskiBBSRC Follow-on Fund in collaboration with John Innes Foundation, A simple, genome-editable technology for inducing steeper, deeper root growth in crops, (09/05/2019) - £250,980
  • Christos PliotasBBSRC-NIRG, Deciphering the structural origins of functional multimodality in bacterial mechanosensitive ion chemicals, (02/05/2019) - 574,586
  • Natalia Riobo-Del GaldoBBSRC, Autophagic flux regulation by the cholesterol/H+ antiporter PTCH1, (02/05/2019) - £557,047
  • Michelle Peckham and Co-I Darren TomlinsonBBSRC, Understanding structure and function of the Z-disc in striated muscle, (02/05/2019) - £807,228
  • Michelle PeckhamBBSRC ALERT18, Stimulated Emission Depletion Microscopy (STED) for imaging at high resolution in the Biosciences, (18/04/2019) - £331,278
  • Scott Bowen with Co-Is S.Calaghan, S.Labeit, K.Witte, L.Roberts, and S.WheatcroftMedical Research Council, NIRG, Muscle RING Finger 1 as a signalling hub for muscle atrophy, mitochondrial dysfunction, and insulin resistance in heart failure and diabetes, (11/04/2019) - £791,366
  • Bryan Taylor with Co-Is K. Witte and J.OliverMedical Research Council, NIRG, Exercise Therapy to Improve Clinical Outcomes and Physiological Function in Group 2 Pulmonary Hypertension, (11/04/2019) - £801,777 
  • David Rowlands, awarded a Visiting Professorship to enable Professor James Hogle to visit University of Leeds for a period of 12 months, (04/04/2019) - £36, 992
  • Jennifer TomlinsonRoyal Society Studentship, Inhibition of a protein-protein interaction mediating antibiotic resistance, (21/03/19) - £150,978
  • Sreenivasan PonnambalamRoyal Society International Exchanges Scheme (China), Calcium-dependent signal transduction and gene expression in cardiac cells and tissues, (21/03/19) - £12,000
  • Adrian WhitehouseRoyal Society Challenge Led Grant with University of KwaZulu-Natal and Rhodes University in South Africa, Developing novel therapeutic approaches to Kaposi’s sarcoma, the most common HIV-associated cancer in Sub Saharan Africa, (21/03/19) - £499,192
  • Maria Beger and PhD student James Cant, Ralph Brown Expedition Award with the Royal Geographical Society, Coral Community Demographics: a predictive framework for the long-term viability of subtropical corals, (19/03/19) - £12,500
  • Alistair Curd, Integrated Biological Imaging Network (sponsored by Kings College London, Developing measurement and analysis tools to correct for optical inhomogeneity in thick samples in high-precision light microscopy, (19/03/19) - £13,517
  • Bill Kunin with Co-Is Chris Hassall and Steve SaitBill and Melinda Gates Foundation, BioDAR: Meteorological radar for pest monitoring and management in southern Africa, (19/03/19) -  $100,000 (£75,642)
  • Ioannia DelisMarie-Curie EU Fellowship, (01/03/2019) - €225,000
  • Shaunna BurkeYorkshire Cancer Research, PREHABS: Prehabilitation Radiotherapy Exercise, smoking Habit cessation and Balanced diet Study, (21/02/19) - £194,062
  • Alison Dunn with Co-Is Chris Hassall, Claire Quinn (Environment), Karen Bacon (Geography) and project partnersNERC, Developing evidence based resources and strategies to slow the spread of aquatic INNS through river catchments in Yorkshire, (15/02/19) - £142,000
  • Ralf RichterEU Proof of Concept grantA new instrument to measure molecular and nanoparticle diffusion in thin solvated films, (15/02/19) - €150,000  (£132,000)
  • David Rowlands & Nicola Stonehouse, Generation of virus free Polio vaccine, (15/02/19) - £1,251,500
  • Richard Bayliss (Co-I on a Cancer Research UK award led by Dr Royle at the University of Warwick)Cancer Research UK, Mitotic spindle stability and chromosome missegregation in cancer, (15/02/19) - £1,543,046.75 with £336904.60 to Leeds
  • Ralf Richter and Co-I Bruce Turnbull (Chemistry)Marie Curie ITN, (31/01/19) - £263,760
  • Lisa Collins and Co-Is Helen Miller (FBS), Steve Banwart, Steve Dobbie, Marcelo Valadares Galdos and Pippa Chapman (Environment), the University of Lincoln and the London School of Hygiene and Tropical MedicineNERC, Smart Systems Approaches for Climate Resilient Livestock Production, (31/01/19) - £251,557
  • Tom Bennett, White Rose Collaboration Fund, Grains of future past: using ancient wheat genetic variation to drive crop improvement, (31/01/19) - £11,000
  • Carrie Ferguson and Co-Is Bryan Taylor, Darren Greenwood and Klaus Witte (both Medicine and Health), British Heart Foundation, Objective assessment of fatigue or dysopnea as the mechanism of exercise limitation in heart failure: Implications for individualised therapy, (24/01/2019) - £296,900
  • Scott BowenBritish Council Newton Fund, Workshop on ‘Neuromuscular rehabilitation after Gunshot wounds,’ (17/01/19) - £45,600
  • Maria BegerRARE, Research into conservation planning of marine protected areas with larval dispersal connectivity, (20/12/18) - £17,789
  • Maria BegerEstate of Winifred Violet Scott Charitable Foundation, How the rates of growth, morality & fecundity differ between threatened corals and tropical locations and sub-tropical latitude communities, (20/12/18) - £24,193
  • Chris West, BBSRC Grant, 18-BTT Clean genome editing through the use of nonintegrating T-DNA, (20/12/18) - £201,732
  • Andrea Utley and Co-I Shaunna BurkeNorthern Ballet Ltd Grant, Dance with Adult Learning Disabilities, (20/12/18), - £19,236
  • Andrew SmithJohns Hopkins University 24 month Research Project, Utilising Novel 3-D bioprinting technology to translate in vitro toxicology findings into complex structures, (20/12/18) - $38,408
  • Emanuele Paci and Co-I Bruce Turnbull (Chemistry)Leverhulme Trust studentship, Rational design of dynamic molecules for enhanced multivalent binding, (06/12/18) - £248,699
  • Richard Bayliss and Co-I Emanuele PaciBBSRC, ‘Helixswitch’, (06/12/18) - £881,614 (£640,001 to Leeds and £241,613 to collaborators at Kings College London)
  • Morgan HerodMRC 5-year Career Development Award Fellowship, Functions of Norovirus VP1: A multi-faceted capsid protein, (06/12/18) - £1,281,713
  • Beatrice Filippi, MRC 5-year Career Development Award Fellowship, Insulin Sensing in the Brain and the effects of Insulin resistance on metabolic behaviour, (06/12/18) - £1,220,695
  • Andrew Smith, John Colyer, Karen PorterHeart Research UK Grant, Detecting hidden biomarkers to investigate and diagnose diabetic vascular pathology, (29/11/18) - £114,992
  • Adrian Whitehouse (Co-I)The Academy of Medical Sciences, Newton Advanced Fellowship, (29/11/18) - £101,000
  • Simon WalkerThe Royal Society, Neuromuscular control and functional mechanics of flight initiation in insects, (22/11/18) - £152,325
  • Maria BegerNERC, Gradients of marine biodiversity and linkages with eDNA across the Wallacea region, (22/11/18) - £353,801
  • Scott Bowen, The Great British Sasakawa Foundtion, Collaboration with University of Kobe on oxygen exchange in the diaphragm and impact of ageing, (22/11/18) - £2,500
  • Steve Clapcote, Amanda Bretman, David Lewis and Elwyn Isaac, NC3Rs, Development of an invertebrate model of alternating hemiplegia of childhood, (15/11/18) - £90,000 
  • Julie Aspden and Juan Fontana, BBSRC, Function and structure of specialised ribosomes in the testis, (8/11/2018) £737,427
  • Paul Millner and the University of CambridgeCancer Research UK Early Detection Programme award, Epigenetic enrichment of circulating tumour DNA to enable deep profiling for cancer early detection, (18/10/18) - £34,781
  • Andrew Smith, Vas Ponnambalam, Mark Drinkhill, BHF, Identifying VEGFR roles in cardiac stem cell contribution to new vascular cell formation, (4/10/18) - £97,478
  • Lars Jeuken, BBSRC, Biohybrids for Solar Fuels: Whole-cell Photocatalysis by Non-Photosynthetic Organisms, (20/9/18) - £345,489 
  • Chris West, BBSRC, Improving germination performance through a mechanistic understanding of seed priming, (20/9/18) - £445,693
  • Nick Plant, Horizon 2020 EU Consortium Bid, Metabolic effects of Endocrine Disrupting chemicals: novel testing Methods and adverse outcome pathways - (20/9/18) - €5,980,408 (€401,031 to Leeds)
  • Nikita Gamper, Wellcome Trust Investigator Award, Peripheral gate in somatosensory system, (13/9/18) - £1,141,006
  • Chris Hassall, Liz Duncan, Bill Kunin, Robin Lovelace, Ryan Neeley III and University of Exeter, NERC, Dual-Polarisation Weather Radar for Advanced Monitoring of Aerial Biodiversity (BioDAR) - (13/9/18), £607,144
  • Lars Jeuken, BBSRC (Pathfinder), Hydrogenase biomembrane-modified anodes for hydrogen-oxygen fuel cells, (13/9/18), £10,657
  • Peter Stockley, BMA Foundation for Medical Research, Human Rhinovirus Assembly as a Novel Drug Target, (13/9/18), £49,102
  • Simon Goodman, US Marine Mammal Commission, Developing solutioins to the critical threat of bycatch in illegal fisheries for Caspian seals (Pusa caspica). (Jul 2018), £34,781
  • Andrew Macdonald, Stephen Griffin, colleague in FMH and University of Birmingham, MRC, HPV hikacking of the epidermal growth factor receptor via its oncogenic ion channel, the E5 viroporin: a new mechanism of virus-driven pathogenesis. (Jul 2018), £588,731
  • Mark Harris, MRC, Hepititis C virus genotypes 3 NS5A protein: resistance to direct acting antiviral agents and functional analysis. (Jul 2018), £543,552
  • Ioannis DelisPhysiological Society, Neural and behavioural mechanisms of active multisensory decision making. (Jul 2018), £10,000
  • Scott BowenPhysiological Society, Establishing an experimental model of skeletal muscle myopathy consequent to diabetic heart failure. (Jul 2018), £10,000
  • Steve Clapcote, Jamie JohnstonThe Dunhill Medical Trust, Effects of specific inhibition of PDE4B on age related cognitive decline’. (Jun 2018), £254,874
  • Adrian GoldmanMRC, Novel Fc mutants to co-opt or avert discrete FcgR functions in therapeutic antibody design’ . (Jun 2018), £98,627
  • Darren Tomlinson, Michelle Peckham, Megan WrightBBSRC, Direct labelling of proteins using Affirmer-conjugate warheads for imaging’ . (Jun 2018), £150,443
  • Simon WalkerRoyal Society, Extension to Research Fellowship. (Jun 2018), £337,601
  • Tom ThirkellN8 Agrifood, The genetic basis of mycorrhizal growth response in spring wheat. (Jun 2018), £14,870
  • Stephen Muench with Glaxo SmithKline & UCB CelltechBBSRC Industrial Partnership Award, The role of closely-associated lipids in membrane protein structure and function. (Apr 2018), £480,225
  • Steve ClapcoteBBSRC, Effects on specific inhibition of PDE4B on senescence-associated cognitive decline. (Apr 2018), £443,072
  • Helen MillerInnovate UK, Centre for Innovation Excellence in Livestock award. (Apr 2018), £999,960
  • Elisabetta Groppelli, David Rowlands & Stanley Lemon (University of North Carolina)Medical Research Foundation Fellowship, Elucidating the mechanism of hepatitits A virus initiation of infection. (Apr 2018), £293,494
  • Nikesh PatelMedical Research Foundation fellowship, In situ structural and mechanistic interrogation of dsDNA synthesis in Hepatitis B virus. (Apr 2018), £290,976
  • Graham Askew with colleagues in Hull and LiverpoolBBSRC, A new framework for computational biomechanical models and 3Rs in musculoskeletal research.. (Apr 2018), £150,498
  • Andrew Macdonald, Neil Ranson & Richard FosterKidney Research UK, Towards the development of entry inhibitors of BK polyomavirus to treat PVAN. (Apr 2018), £82,821
  • Jessica Kwok & Ralf RichterLeverhulme Trust, Biopolymer physics defines perineuronal net morphology and synapse formation. (Apr 2018), £298,273
  • Julie AspdenRoyal Society, Structure and function of neuronal specialised ribosomes. (Apr 2018), £20,000
  • Liz DuncanRoyal Society, Maternal control of early development in the non-model insect pest Acyrthosiphon pisun (pea aphid). (Mar 2018), £14,602
  • Alex O'Neill & Ryan SeipkeBBSRC, BBSRC NPRONET. (Feb 2018), £45,489
  • Jim DeucharsRoyal Society, Translational grant to develop a prototype transcutaneous vagal nerve simulator based on public and patient interaction. (Feb 2018), £16,300
  • Stefan Kepinski & Netta CohenLeverhulme Trust, Towards the formulation of a general theory of root gravitropism. (Feb 2018), £320,387
  • Lisa CollinsBBSRC, International Partnering Award. (Feb 2018), £49,950
  • Alison BakerBBSRC , International Partnering Award. (Feb 2018), £30,000
  • Nikita GamperBBSRC, International Partnering Award. (Feb 2018), £30,000
  • Lars JeukenBBSRC, International Partnering Award. (Feb 2018), £30,000
  • Scott BowenLeducq Foundation Grant, Mechanical Triggers to Programmed Cell Death in Cardiomyocytes and how to prevent their action in failing hearts.. (Feb 2018), £28,470
  • Jessica Kwok and Ronaldo IchiyamaInternational Spinal Research Trust, Oral Administration of a novel plasticity enhancer improves functional recovery after chronic spinal cord injury. (Feb 2018), £94,450
  • Alex O'NeillOxford Drug Design, Studies to elucidate the mechanism of action, resistance frequency and broader microbiological profile on novel tRNA synthetase inhibitors. (Jan 2018), £86,098
  • Dave Lewis and Colleagues in South AfricaHEFCE Global Challenge Research, Building capacity for pre-clinical research and drug discovery in South Africa: A continuing professional development course for research animal vets. (Jan 2018), £48,000
  • Sarah Calaghan, Ed White, John Colyer, Isuru JayasingheBHF, The caveolar coat complex as a mediator of mechano-sensation in the heart. (Jan 2018), £128,308
  • Christine Foyer and Alison BakerHEFCE GCRF Grant, Foster partnerships to optimise sustainable intercropping systems in African agriculture. (Jan 2018), £71,158
  • Alison Baker, Yun Yung Gong and Lindsay Stringer and ICRISAT IndiaHEFCE GCRF Grant, Workshop on "Plant Science for Food Security and Nutrition". (Jan 2018), £27,000
  • Graham Askew, Simon WalkerBBSRC, An integrated approach towards characterising the functional mechanics and energetics of insect flight muscles. (Jan 2018), £699,781
  • Jennifer TomlinsonRoyal Society, Dorothy Hodgkin Research Fellowship. (Jan 2018), £512,801
  • Alison DunnNERC, Biosecurity to Slow the spread of Invasive Species. (Dec 2017), £18,000
  • Jennifer TomlinsonRoyal Society-Research Fellows Enhancement Award, Understanding the role of allostery in antibiotic resistance. (Dec 2017), £94,681
  • Helen MillerAB AGri Grant, Additional funding. (Dec 2017), £73,600
  • Simon WalkerRoyal Society Enhancement Award, Imaging insect flight. (Dec 2017), £10,000
  • Carrie Ferguson, Bryan Taylor, Harry RossiterThe Physiological Society, Workshop: Cardiopulmonary exercise testing and interpretation. (Dec 2017), £7,392
  • Ralf RichterRoyal Society, Cell adhesion to soft substrates under flow - physical mechanisms of cell homing at the blood vessel wall. (Dec 2017), £6,000
  • Christine FoyerBritish Council Newton Fund, Trilateral workshop between UK, South Africa and Kenya. (Dec 2017), £49,840
  • Adrian Whitehouse and colleagues in School of Chemistry and University of LiverpoolMRC, Targeting the RNA helicase, UAP56. (Nov 2017), £622,319
  • Michelle Peckham, Neil RansomMRC, How do mutations in non-muscle myosin 2A cause bleeding disorders and other defects?. (Nov 2017), £495,159
  • Dave LewisBritish Council India, Developing and sustaining India's capacity for pre-clinical drug discovery. (Nov 2017), £22,540
  • Elton ZeqirajRoyal Society, Understanding the structure of glycogen synthase-glycogenin initiating complex during glucose storage and metabolism. (Nov 2017), £15,000
  • Hannah DugdaleRoyal Society, Isolation by distance in the cooperatively breeding acorn woodpecker. (Nov 2017), £15,000
  • Shaunna BurkeCancer Research UK Innovation Grant, Investigating the feasibility and acceptability of geocaching for promoting physical activity in childhood cancer patients and their families. (Nov 2017), £20,000
  • Alex O'Neill and colleagues in ChemistryBBSRC, Understanding antibiotic entry into bacteria. (Nov 2017), £431,865
  • Jessica KwokWings for Life, CSPG inhibition and spinal cord injury. (Nov 2017), £87,365
  • Tom BennettBBSRC, Pathways to neo-functionalization: the past and future of strigolactone signalling. (Oct 2017), £523,679
  • Neil Ranson, Darren TomlinsonBBSRC, Exploiting the power of heterologous expression in plants to discover new virus structure. (Oct 2017), £494,318
  • Nikita GamperBBSRC, Junctional multiprotein signalling complexes in sensory neurons. (Oct 2017), £490,426
  • Amanda Bretman and colleagues from UEANERC, Measure for measure: female responses to the social and sexual environment. Total award to Leeds £7,813. (Oct 2017), £430,886
  • Juan FontanaRosetrees Trust consumables grant, Understanding how Influenza virus enters cells to start an infection. (Oct 2017), £22,500
  • Helen MillerDSM Nutritional Products AG, effect of three levels of RONOZYME HiPhos on the performance, digestibility and bone strength of growing and finishing swine fed diets differing in the content of calcium and phosphorus. . (Sep 2017), £69,988
  • Neil Ranson, Juan Fontana, Mark Harris, Michelle Peckham, Ralf Richter, Peter Stockley, Patricija Van Oosten-Hawle and colleagues in Engineering, FMH and MAPSWellcome Trust Equipment Call, Bridging the gap between cell and structural biology at the University of Leeds. (Sep 2017), £418,000
  • Jamie JohnstonPhysiological Society, How does feeding state alter the representation of odours in the olfactory bulb?. (Sep 2017), £10,000
  • Frank Sobott, Adrian Goldman, Mark Harris, Andrew Macdonald, Stephen Muench, Sheena Radford and colleagues in FMH and MAPSWellcome Trust Equipment Call, Enabling novel research lines and building mass spectrometry capacity for structural biology and translational medicine. (Aug 2017), £415,000