Dr Emma Hesketh

Dr Emma Hesketh


I joined the University of Leeds in 2014 as a Post-doctoral research scientist in Professor Neil Ranson's group. In 2017 I joined the Electron Microscopy facility as a Cryo-EM Support Scientist on a part-time basis. My current role is 70% Cryo-EM Support scientist and and 30% Post-doctoral research scientist.

I obtained my PhD in Biology at the University of York in 2015 following my undergraduate degree in Biochemistry (Ind) at the University of Leeds.

Research interests

My research focuses on the structure of viruses using cryo-electron microscopy to preform single particle 3D reconstructions to high (<3.5Å) resolution. I am particularly interested in how viruses select and package their genomic information to make an infectious virion. As a Support Scientist, my role includes day-to-day running of the Titan Krios electron microscopes, providing guidance, training and advice to users (both internal and external) in areas covering sample preparation, optimisation, freezing, and image optimisation, using both single particle and tomographic methods. I am also involved in pump priming new research for anyone at the University getting started with electron microscopy and I am the main contact for industrial clients wishing to use the electron microscope facilities at Leeds.


  • PhD, University of York, 2015
  • Bsc (Ind) Biochemistry, University of Leeds, 2011

Professional memberships

  • Royal Microscopy Society

Student education

I teach staff, students and visitors how to use the equipment in the Electron Microscopy facility. This includes electron microscopes, cryo-EM grid freezing devices and image processing. I also teach on a PhD module for electron microscopy.