Dr Anna Tang

Profile

I am a translational molecular and cellular biologist with over 20 years' experience spanning academia, biotechnology, diagnostics, and regulated industrial R&D. My work focuses on engineered non-antibody affinity reagents, protein engineering, phage display, and translational research, with a particular interest in developing technologies that address real-world challenges in healthcare and biotechnology.

Since joining the University of Leeds in 2011, I have contributed to the development and application of Adhiron/Affimer technologies, supporting projects ranging from fundamental studies of protein-protein interactions to diagnostic and therapeutic applications. My experience includes affinity reagent discovery and validation, molecular recognition, assay development, cellular signalling, and collaborative research with academic, clinical, and industrial partners.

Alongside my research career, I completed a part-time PhD investigating SH3 domain-mediated protein interactions within Ras signalling pathways, using Affimer technology to probe cellular mechanisms. This work strengthened my expertise in cell signalling and reinforced my interest in applying innovative affinity reagents to address biological questions.

I currently work within Professor Darren Tomlinson's research group on projects focused on the commercialisation of Adhiron technology. My role combines translational research, intellectual property development, and industry collaboration to support the translation of Adhiron-based technologies into commercially relevant applications.

Earlier in my career, I worked in GLP/GMP and ISO-regulated industrial environments, contributing to biologics development and in vitro diagnostic innovation, including an automated immunoassay platform that achieved CE marking and FDA clearance.

I am motivated by translating fundamental science into practical applications and welcome opportunities for collaboration across academia, biotechnology, diagnostics, and innovation-focused research.

Research interests

Core expertise:

• Engineered affinity reagents (Adhirons/Affimers)
• Phage display and selection strategy design
• Protein engineering and molecular recognition
• Protein-protein interactions and cell signalling
• Diagnostic assay development
• Translational research and technology translation
• Research commercialisation and industry collaboration

Qualifications

• PhD Molecular and Cellular Biology, University of Leeds (2023)
• BSc (Hons) Molecular Biology, Newcastle University (2002)