Professor Nicola Stonehouse

Profile

Research is the Stonehouse group spans virology and RNA biology, applying novel approaches to the study of virus replication and assembly in three main research areas: 

1. Picornaviral replication, especially the role of the RNA-dependent RNA polymerase of foot-and-mouth disease virus and processing of the viral polyprotein. This project is funded by BBSRC.
2. Design of novel virus-like particle vaccines (e.g. to polio and EV71) and design of generic vaccine scaffold systems. This project is funded by MRC and by WHO
3. RNA aptamers as tools and delivery of aptamers into the skin as potential novel therapeutics. This project is funded by MRC.

Research interests

Viral replication and assembly

• Live cell imaging capability for research on pathogenic viruses
• Mass spectrometry infrastructure for in-cell structural biology

Qualifications

• BSc, UEA; PhD 1992, Leeds.
• PGCLTHE
• FRSB

Professional memberships

• Microbiology Society
• Biochemical Society

Student education

Postgraduate studentship areas:

• Picornaviral replication
• Virus-like particle vaccine development
• Use of RNA aptamers to study viral proteins and inhibit their function

See also:

• Faculty Graduate School
• FindaPhD Project details:
  • Project 2662
  • Project 41347
  • Project 41271

Modules managed

BIOL3400 - Skills in the Cell Biology of Human Disease

Modules taught

BIOC1301 - Introductory Integrated Biochemistry: the Molecules and Processes of Life
BIOC3111/12/BIOL3112/MICR3120 A - ATU - Visualising Viruses
BIOC3160 - Laboratory/Literature/Computing Research Project
BIOL2301 - Intermediate Skills for Biological Sciences
BIOL2301/03 - Intermediate Skills - BIOL
BIOL3306 - Biological Sciences Research Project
BIOL3399 - Extended Research Project Preparation
BIOL3400 - Skills in the Cell Biology of Human Disease
BIOL5180M - Biopharmaceutical Drug Discovery and Pre-clinical testing
BIOL5294M - MSc Bioscience Research Project Proposal
BIOL5296M - Treatment of Infectious Disease and Cancer
BIOL5382M - Extended Research Project
BIOL5392M - Bioscience MSc Research Project
BIOL5394M - Specialised Research Topics and Skills
BIOW5902X - Medicinal Chemistry and Drug Design
BLGY3110 - Applied Genetics
BMSC2120 - Scientific Skills
MICR1120 - Introduction to Microbiology
MICR2121 - Molecular Virology
MICR2222 - Medical Virology
MICR3110 - Medical Microbiology Research Project
MICR3120/BIOC3111/12/BIOL3112 A - ATU - Respiratory infections
MICR3343 - Skills for Microbiology in Relation to Medicine

Academic roles

UG Programme Leader - MCB intercalated programmes

Committees

Member of Undergraduate School Taught Student Education Committee