Electron Microscopy

We are pleased to offer our services to industry clients who would like to utilise cryo-EM as part of their structural biology endeavours. Our expert staff are available to advise and assist at all stages of the cryo-EM pipeline, offering support for a range of projects from investigation of small molecule binding to nanoparticle characterisation.

Available services:

• Quick and informative quality control assessment of samples by negative stain TEM
• Cryo-EM grid preparation using Leica EM-GP or Vitrobot mark IV
• Cryo-EM grid screening
• Automated data acquisition
• Image processing and data analysis

Our facility houses a range of state-of-the-art equipment to support the delivery of your projects, including our two Titan Krios microscopes equipped with Falcon 4i detectors. To browse the full range of equipment available, please see the equipment and services section of our webpage.

To get started, or to find out how we can help with your project, contact us at cryoEM@leeds.ac.uk.