Macromolecular X-ray Crystallography

Equipment

Nt8 lcp crystallisation

 

Protein crystallisation screen liquid handler

  • Formulator (FormulatrixÒ)

Robotic crystallisation system  

  • NT8 LCP drop setter (FormulatrixÒ)
  • Mosquito Crystal (ttplabtech)

Crystallisation imaging system (FormulatrixÒ)

  • Rock Imager 1000 at 20°C with Second Order Nonlinear Imaging of Chiral Crystals (SONICC) imaging.
  • Rock Imager 1000 at 4 °C with UV imaging.
  • Fluorescence Recovery After Photobleaching (FRAP) imaging to Identify the optimal conditions for Lipidic Cubic Phase crystal growth for membrane protein crystallography.

X-ray diffraction data collection is available at both the Diamond Light Source Ltd, Oxfordshire and the European Synchrotron Radiation Facility, France.