Affimer Applications

Formation of Magnetic Nanoparticle

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Development of an Affimer-antibody combined immunological diagnostic kit for glypican-3. Xie C, Tiede C, Zhang X, Wang C, Li Z, Xu X, McPherson MJ, Tomlinson DC, Xu W. Sci Rep. 2017 Aug 29;7(1):9608. doi: 10.1038/s41598-017-10083-w.

Affimer proteins are versatile and renewable affinity reagents. Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, AlQallaf D, Roberts AP, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC. Elife. 2017 Jun 27;6. pii: e24903. doi: 10.7554/eLife.24903. 

Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. C Tiede, A Tang, S Deacon, U Mandal, J Nettleship, D Harrison, R Owen, R Owens, S George, D Tomlinson, M McPherson. Protein Eng Des Sel. 2014 May;27(5):145-55.