Affimer Applications

Detection of Small Molecules

Affimer proteins are versatile and renewable affinity reagents. Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, AlQallaf D, Roberts AP, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC. Elife. 2017 Jun 27;6. pii: e24903. doi: 10.7554/eLife.24903. 

Interfacing native and non-native peptides: using Affimers to recognise α-helix mimicking foldamers. Arrata I, Barnard A, Tomlinson DC, Wilson AJ. Chem Commun (Camb). 2017 Mar 2;53(19):2834-2837. doi: 10.1039/c6cc09395g.

Antibody Mimetics for the Detectiosn of Small Organic Compounds Using a Quartz Crystal Microbalance. Koutsoumpeli E, Tiede C, Murray J, Tang A, Bon RS, Tomlinson DC, Johnson S.  Anal Chem. 2017 Mar 7;89(5):3051-3058. doi: 10.1021/acs.analchem.6b04790.