Our facility has a range of light microscopes to cater for a large variety of applications.
These range from widefield fluorescent systems and confocal microscopes through to super-resolution systems.
We have the capability to image both fixed and live samples to facilitate the investigation of a wide range of biological questions.
Our range of widefield fluorescence microscopes enable us to image a variety of samples from high-resolution imaging of fixed or live cells to high-throughput imaging of slides and the imaging of whole tissues.
Confocal laser scanning microscopes utilises a pinhole to block out-of-focus light and improve image resolution.
Our high-end systems are capable of 2D and 3D imaging of fixed and live samples.
We offer and range of confocal microscope of suite a variety of sample types.
Super Resolution Microscopy
The resolution that can be achieved by traditional light microscopy is limited by the diffraction of light, which sets the shortest distance distinguishable between two points at ~half the wavelength of light (>200nm).
There are a diverse range of fundamental cellular processes the take place below the resolution limit of light and fluorescence microscopy.
Super resolution microscopy uses a number of techniques to push beyond the 200nm barrier to enable the study of cellular structure and dynamic processes that couldn’t previously be imaged by standard imaging techniques.
Fluorescent super-resolution techniques enable highly specific, multi-colour imaging of both live and fixed cells.
The facility has 2 dedicated image analysis stations giving access to a range of software including; Imaris, Zen, ImSpector, ImageJ/FIJI, ICY.