Bio-imaging equipment

Zeiss LSM880 + Airyscan Inverted Confocal Microscope

Confocal microscope for the imaging of both fixed and live cells. The inverted set-up enables samples to be imaged in a variety of holders including slides, chamber slides, imaging dishes or imaging plate formats.  


  • Fully automated inverted microscope.
  • Improved resolution in x, y and z, higher sensitivity and increased speed
  • Spectral imaging and linear un-mixing capabilities to allow the differentiation of similar fluorescence dyes or fluorescence signals from auto-fluorescence.
  • Sensitive GaAsp detectors allow you to use less laser power, performing gentle imaging of your samples
  • Motorised stage for screening plates and slides, tile scanning and point visiting
  • Piezo stage for faster and more accurate Z-stacks and 3D imaging
  • Temperature and CO2 regulation for live cell imaging with heated stage and fully integrated incubator box
  • FRAP and FRET imaging including FRAP analysis module
  • FCS (Fluorescence correlative spectroscopy) capabilities
  • 1.7x higher resolution in all three dimensions with Fast Airyscan, compared to conventional confocal microscopy


  • Axio Observer.Z1
  • Nano Focusing Piezo Stage
  • ZL multi S1 Incubator box (Temperature and CO2)
  • Heated stage insert (Temperature and CO2)


  • Diode 405 nm
  • Argon 458, 488, 514 nm
  • DPSS 561 nm
  • HeNe 633 nm


  • EC Plan-Neofluor 10x/0.30
  • Plan-Apochromat 20x/0.8
  • C-Apochromat 40x/1.2 W Korr FCS (available on request)
  • Plan-Apochromat 40x/1.4 Oil DIC
  • Plan-Apochromat 63x/1.4 Oil DIC

PMTs and Emission Filters

  • 2 PMTs plus additional GaAsp detector with fully 'tunable' emmision collection
  • Fast Airyscan module for 1.7x increased resolution with the following emission filters:
    • BP420-480 + BP495-550
    • BP420-480 + BP495-620
    • BP420-480 + LP605
    • BP465-505 + LP525
    • BP495-550 + LP570
    • BP570-620 + LP645


Faculty of Biological Sciences, L.C.Miall 5.08