Biotechnology themes
Developing Biopharmaceuticals
Biopharmaceuticals are defined as biological macromolecules or cellular components that are extracted or synthesised from biological sources that can be used as a therapy or in diagnostics.
Members of our school with expertise in molecular biophysics, structural biology, virology and microbiology have key interests in exploiting their research for improved biopharmaceutical manufacture.
Work in this area ranges from the development of precision drugs using either chemical compounds or macromolecules, understanding protein folding towards ensuring biopharmaceutical stability and safety, the application of Affimer reagents to intervene in biological pathways, and the study of viruses to develop vaccines against outbreaks that can damage both human and agricultural populations.
More detail can be found through the individual staff profiles listed below.
View our academics within Developing Biopharmaceuticals
View our postdoctoral researchers within Developing Biopharmaceuticals
View our PhD students within Developing Biopharmaceuticals
|
Name |
Area of expertise |
|
Professor Richard Bayliss |
Nanobodies and peptide-based inhibitors of enzymes and protein-protein interactions |
|
Dr David Brockwell |
Biophysical analysis of aggregation mechanisms of proteins and biopharmaceuticals |
|
Professor Michael McPherson |
Investigation of Affimer proteins as therapeutic interventions particularly related to anti-microbial resistance |
|
Professor Sheena Radford |
Biophysical analysis of aggregation mechanisms of proteins and biopharmaceuticals |
|
Professor David Rowlands |
Generation and characterisation of virus-like particles as novel vaccines and vaccine scaffolds |
|
Dr Ryan Seipke |
Unlocking the expression of cryptic microbial biosynthetic pathways to discover novel chemical scaffolds |
|
Prof Frank Sobott |
Using mass spectrometry methods to investigate protein structure from sequence to folding and interactions. |
|
Professor Nicola Stonehouse |
Generation and characterisation of virus-like particles as novel vaccines and vaccine scaffolds |
| Dr Darren Tomlinson Associate Professor |
Development of Affimer reagents as biopharmaceuticals for treating diseases |