Cancer

Ruffling cell image by Michelle Peckham

Cancer

Our research

We study the molecular and cellular basis of cancer and the development of target-specific therapeutics.

Our research ranges from analysis of genomes and transcriptomes in cancer, structural biology and dynamics of cancer regulatory pathways, and mechanistic understanding of intracellular and inter-cellular signalling to aberrant tissue homeostasis, the biology of viruses that cause cancer and screening and design of potential therapeutic leads.  

Research themes

Understanding the structure of oncogenes and cancer growth regulatory proteins and the mechanistic basis of aberrant intra- and inter-cellular communication.

More on Cell Signalling

Understanding cancer cells behaviour and cytoskeletal organisation, the role of the tumour stroma and the control of tumour angiogenesis.

More on Tumour Biology
Differential gene expression in haematological malignancies Polycytemia Vera (PV) and Essential Thrombocytemia (ET)

Understanding genomic and epigenomic changes that drive cancer biology

Understanding the mechanisms of virus-induced cancer development.

More on Viral Oncology

Screening and optimisation of small molecules and peptide-based diagnostic and therapeutic compounds.

More on Cancer Therapeutics