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Cancer research themes

Cell Signalling

Crystal structure of Aurora-A (cyan) in complex with N-Myc residues 61–89 (red). (Courtesy of Prof. Richard Bayliss)

Crystal structure of Aurora-A (cyan) in complex with N-Myc residues 61–89 (red). (Courtesy of Professor Richard Bayliss)

View a list of academics within Cell Signalling

View a list of postdoctoral researchers within Cell Signalling

View a list of PhD students within Cell Signalling

Name	Area of expertise
Professor Richard Bayliss Professor in Molecular Medicine	Structural mechanisms of regulation in kinase pathways that control proliferation, transcription and cell division
Professor Alex Breeze Chair in Biomolecular NMR	Structural and dynamic mechanisms of signal transduction and inhibition in fibroblast growth factor receptors
Dr Edwin Chen University Academic Fellow	Our lab aims to understand the role of aberrant JAK-STAT signalling on leukaemic stem cell activity in the pathogenesis of haematological malignancies
Dr. Joe Cockburn Lecturer	Understanding primary cilia and microtubule transport using structural biology
Dr Aysha Divan Associate Professor	Cell signalling in epithelial cancers
Dr Thomas Edwards Associate Professor	Protein-protein interactions of the Bcl family of apoptosis-regulatory proteins
Professor John Ladbury Professor of Mechanistic Biology	Structural and mechanistic basis of pathological signal transduction by receptor tyrosine kinases
Dr Andrew Macdonald Associate Professor in Virology	We are interested in understanding cross-communication between pathways that regulate cellular homeostasis and how these are perturbed in cancer
Dr. Takashi Ochi University Academic Fellow	Structure-based molecular assembly mechanisms of centrosomes and cilia
Dr Natalia Riobo-Del Galdo University Academic Fellow	Molecular mechanisms of canonical and non-canonical Hedgehog signal transduction
Professor Sreenivasan Ponnambalam Reader in Human Disease Biology	Receptor tyrosine kinase signal transduction in primary and transformed cells
Dr Darren Tomlinson Associate Professor	Understanding cellular signalling by modulating protein function and protein-protein interactions using Affimer reagents
Dr Stephanie Wright Senior Lecturer	Cancer biology; targeted cancer therapies; eukaryotic gene regulation; protein ubiquitination; structural biology
Dr. Qian Wu University Academic Fellow	Structural mechanisms of human DNA repair pathways
Dr Elton Zeqiraj Sir Henry Dale Fellow	Control of cell signalling networks by ubiquitin